Podcasts and conversations

I host Immortal Combat, a podcast about longevity. Since 2024, I’ve been talking with researchers, physicians, founders, and people working to extend healthy life.

Start with my conversation with Annie Nosh. Other conversations include Matt Kaeberlein and Dave Pascoe.

Browse the official episode playlist or visit my YouTube channel.

Selected longevity conversations

Annie Nosh: Published 19 August 2025
Her path into longevity, daily routines, and what she learned through trial and error.
Matt Kaeberlein: Published 18 September 2025
Aging research, rapamycin, scientific incentives, and the need for discovery science.
Dave Pascoe: Published 20 August 2024
His approach to longevity, daily routines, and life as a hacker and biohacker.
Lucas Aoun: Published 27 September 2026
Hormones, laboratory measurements, and testosterone.
Irina and Michael Conboy: Published 13 September 2026
Plasma dilution, systemic aging, and the limitations of biological-aging clocks.
Liz Parrish: Published 4 July 2026
Gene therapy, telomeres, and her experience with BioViva.
Joy Kong: Published 27 June 2026
Stem-cell therapy, the evidence behind it, and the questions around its use.
Aubrey de Grey: Published 25 April 2026
Longevity escape velocity, mouse studies, and the evidence aging research still needs.
Klaus Townsend: Published 7 February 2026
Longevity as a sport and what biological-aging clocks measure.
Alan Graves: Published 15 July 2025
Supplement quality, biological-age testing, and funding longevity research.
Julie Gibson Clark, Dave Pascoe, and Siim Land: Published 22 September 2024
A panel on aging, competition, and different approaches to health.
Michael Lustgarten: Published 13 August 2024
Tracking biomarkers, testing changes, and the limits of published studies.
Oliver Zolman: Published 17 April 2024
Biological-age measurement, the Rejuvenation Olympics, and longevity competitions.

Pursuit of Value with Derek Mazzone

My 2023 conversation series with Derek Mazzone, author of The Pursuit of Value: A Philosophy of Loss and Equanimity. We discuss method, value, religion, ethics, meaning, and mind.

Full series playlist

Introduction: Published 11 November 2023
Derek Mazzone’s background, his book, and why value matters.
Method: Published 18 November 2023
Pragmatism and philosophical methods.
Value: Published 25 November 2023
What value is and how it relates to the goals of a life.
Religion: Published 2 December 2023
Religion, spirituality, and value.
Ethics: Published 9 December 2023
Meaning: Published 16 December 2023
Mind, part 1: Published 23 December 2023
Existence, thinking, and goals for life.
Mind, part 2: Published 30 December 2023
The final conversation in the series.

Other conversations

Matteo Cassese — Agentic Fever: Published 7 May 2026
AI agents, burnout, context switching, and changing work.
Dave Pascoe — Being a Hacker Before Hacking Was Invented: Published 11 April 2026
From punch cards and early networks to automation and AI.
David Friedman — The World of Strong Privacy: Published 14 June 2021
Encryption, anonymous payments, reputation, and the future of privacy.
Chris Belcher — JoinMarket and light-client privacy: Published 1 March 2018
A conversation about open-source software, JoinMarket, and light-client privacy.
waxwing — Bulletproofs, Monero, and Mimblewimble: Published 25 February 2018
A discussion of zero-knowledge proofs, Bulletproofs, Monero, and Mimblewimble.

Block Digest

Block Digest: I co-hosted this Bitcoin news and technology podcast.
Example episode